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XRN1 (5'-3' exoribonuclease 1)

Identity

Alias_symbol (synonym)02-Sep
Other aliasSEP1
HGNC (Hugo) XRN1
LocusID (NCBI) 54464
Atlas_Id 54788
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 142306607 and ends at 142448062 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NQO1 (16q22.1) / XRN1 (3q23)XRN1 (3q23) / ATR (3q23)XRN1 (3q23) / GNPTAB (12q23.2)
XRN1 (3q23) / PIP4K2A (10p12.2)XRN1 (3q23) / PRKCE (2p21)XRN1 3q23 / PRKCE 2p21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0310q23p12ID105560


External links

Nomenclature
HGNC (Hugo)XRN1   30654
Cards
Entrez_Gene (NCBI)XRN1  54464  5'-3' exoribonuclease 1
AliasesSEP1
GeneCards (Weizmann)XRN1
Ensembl hg19 (Hinxton)ENSG00000114127 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114127 [Gene_View]  ENSG00000114127 [Sequence]  chr3:142306607-142448062 [Contig_View]  XRN1 [Vega]
ICGC DataPortalENSG00000114127
TCGA cBioPortalXRN1
AceView (NCBI)XRN1
Genatlas (Paris)XRN1
WikiGenes54464
SOURCE (Princeton)XRN1
Genetics Home Reference (NIH)XRN1
Genomic and cartography
GoldenPath hg38 (UCSC)XRN1  -     chr3:142306607-142448062 -  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)XRN1  -     3q23   [Description]    (hg19-Feb_2009)
GoldenPathXRN1 - 3q23 [CytoView hg19]  XRN1 - 3q23 [CytoView hg38]
ImmunoBaseENSG00000114127
Mapping of homologs : NCBIXRN1 [Mapview hg19]  XRN1 [Mapview hg38]
OMIM607994   
Gene and transcription
Genbank (Entrez)AK096177 AK123897 AK304312 AL117516 AL133623
RefSeq transcript (Entrez)NM_001042604 NM_001282857 NM_001282859 NM_019001
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)XRN1
Alternative Splicing GalleryENSG00000114127
Gene ExpressionXRN1 [ NCBI-GEO ]   XRN1 [ EBI - ARRAY_EXPRESS ]   XRN1 [ SEEK ]   XRN1 [ MEM ]
Gene Expression Viewer (FireBrowse)XRN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)54464
GTEX Portal (Tissue expression)XRN1
Human Protein AtlasENSG00000114127-XRN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)XRN1
DMDM Disease mutations54464
Blocks (Seattle)XRN1
Human Protein Atlas [tissue]ENSG00000114127-XRN1 [tissue]
HPRD10470
IPIIPI00657805   IPI00657645   IPI00328115   IPI00792899   IPI00946262   IPI00979282   IPI00944901   
Protein Interaction databases
FunCoupENSG00000114127
BioGRIDXRN1
STRING (EMBL)XRN1
ZODIACXRN1
Ontologies - Pathways
Huge Navigator XRN1 [HugePedia]
snp3D : Map Gene to Disease54464
BioCentury BCIQXRN1
ClinGenXRN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54464
Chemical/Pharm GKB GenePA134878471
Clinical trialXRN1
Miscellaneous
canSAR (ICR)XRN1 (select the gene name)
DataMed IndexXRN1
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineXRN1
EVEXXRN1
GoPubMedXRN1
iHOPXRN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 19 17:16:54 CET 2020

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