YBX3 (Y-box binding protein 3)

2007-02-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
CSDA,CSDA1,DBPA,ZONAB
FUSION GENES

Other Information

Locus ID:

NCBI: 8531
MIM: 603437
HGNC: 2428
Ensembl: ENSG00000060138

Variants:

dbSNP: 8531
ClinVar: 8531
TCGA: ENSG00000060138
COSMIC: YBX3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000060138ENST00000228251P16989
ENSG00000060138ENST00000228251A0A024RAQ1
ENSG00000060138ENST00000279550P16989
ENSG00000060138ENST00000279550A0A024RAV4
ENSG00000060138ENST00000544622A0A0D9SEI8

Expression (GTEx)

0
500
1000
1500
2000
2500

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
165080132006Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA.79
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
201334802010ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells.39
147286922004A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization.31
248859292014Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression.22
193287952009The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1.17
227118222012Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival.13
122396252002Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis.10
197497852009Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells.7
214736842011Critical roles of cold shock domain protein A as an endogenous angiogenesis inhibitor in skeletal muscle.6

Citation

Dessen P

YBX3 (Y-box binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45758/ybx3