YKT6 (YKT6 v-SNARE homolog)

2007-10-01  

Identity

HGNC
LOCATION
7p13
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 10652
MIM: 606209
HGNC: 16959
Ensembl: ENSG00000106636

Variants:

dbSNP: 10652
ClinVar: 10652
TCGA: ENSG00000106636
COSMIC: YKT6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106636ENST00000223369O15498
ENSG00000106636ENST00000223369A4D2J0
ENSG00000106636ENST00000424864H7C3K7
ENSG00000106636ENST00000496112O15498

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
123887522002GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus.50
118843502002Abnormalities of SNARE mechanism proteins in anterior frontal cortex in severe mental illness.42
297894392018Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17.28
272859872016YKT6 expression, exosome release, and survival in non-small cell lung cancer.26
168210822007Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers.24
146079372003Mast cell degranulation requires N-ethylmaleimide-sensitive factor-mediated SNARE disassembly.19
300104602018A membrane fusion protein, Ykt6, regulates epithelial cell migration via microRNA-mediated suppression of Junctional Adhesion Molecule A.2
316488982019Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein.0

Citation

Dessen P

YKT6 (YKT6 v-SNARE homolog)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49756/ykt6