Identity
HGNC
LOCATION
4q13.2
LOCUSID
ALIAS
YT521,YT521-B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91746
MIM: 617283
HGNC: 30626
Ensembl: ENSG00000083896
Variants:
dbSNP: 91746
ClinVar: 91746
TCGA: ENSG00000083896
COSMIC: YTHDC1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37917328 | 2024 | Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia. | 2 |
| 38224863 | 2024 | KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells. | 0 |
| 38566554 | 2024 | YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer. | 1 |
| 38573528 | 2024 | YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus. | 0 |
| 38745192 | 2024 | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation. | 1 |
| 37917328 | 2024 | Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia. | 2 |
| 38224863 | 2024 | KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells. | 0 |
| 38566554 | 2024 | YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer. | 1 |
| 38573528 | 2024 | YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus. | 0 |
| 38745192 | 2024 | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation. | 1 |
| 36302453 | 2023 | Downregulation of the m(6)A reader protein YTHDC1 leads to islet β-cell failure and diabetes. | 6 |
| 36780989 | 2023 | YTHDC1 maintains trophoblasts function by promoting degradation of m6A-modified circMPP1. | 3 |
| 36819785 | 2023 | The Effect of N6-Methyladenosine Regulators and m6A Reader YTHDC1-Mediated N6-Methyladenosine Modification Is Involved in Oxidative Stress in Human Aortic Dissection. | 2 |
| 36878322 | 2023 | Reduction of mRNA m(6)A associates with glucose metabolism via YTHDC1 in human and mice. | 4 |
| 36906205 | 2023 | Alternative splicing of HOXB-AS3 underlie the promoting effect of nuclear m6A reader YTHDC1 on the self-renewal of leukemic stem cells in acute myeloid leukemia. | 7 |
Citation
Dessen P
YTHDC1 (YTH domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-11-01
Online version: http://atlasgeneticsoncology.org/gene/51760/ythdc1
