ZAR1 (zygote arrest 1)

2010-12-01 Affiliation

Identity

HGNC

ZAR1

LOCATION

4p11

LOCUSID

326340

ALIAS

Z3CXXC6

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 326340
MIM: 607520
HGNC: 20436
Ensembl: ENSG00000182223

Variants:

dbSNP: 326340
ClinVar: 326340
TCGA: ENSG00000182223
COSMIC: ZAR1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000182223	ENST00000327939	Q86SH2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
24787227	2014	Evaluation of ZAR1 and SFRP4 methylation status as potentials biomarkers for diagnosis in cervical cancer: exploratory study phase I.	5
28791558	2017	ZAR1 knockdown promotes the differentiation of human neuroblastoma cells by suppression of MYCN expression.	1
12773403	2003	Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries.	0
16551357	2006	Zygote arrest 1 gene in pig, cattle and human: evidence of different transcript variants in male and female germ cells.	0
20654783	2010	Identification and analysis of an early diagnostic marker for malignant melanoma: ZAR1 intra-genic differential methylation.	0
21206179	2010	Aberrant hypermethylation of non-promoter zygote arrest 1 (ZAR1) in human brain tumors.	0
23583134	2013	Non-promoter DNA hypermethylation of Zygote Arrest 1 (ZAR1) in neuroblastomas.	0
25227574	2015	Identification of frequent differentially methylated region in sporadic bladder cancers.	0
28588743	2017	ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer.	0

Citation

Dessen P

ZAR1 (zygote arrest 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-12-01

Online version: http://atlasgeneticsoncology.org/gene/51773/zar1