| Nomenclature |
|---|
| HGNC (Hugo) | ZBTB4 23847 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ZBTB4 57659 zinc finger and BTB domain containing 4 |
| Aliases | KAISO-L1; ZNF903 |
| GeneCards (Weizmann) | ZBTB4 |
| Ensembl hg19 (Hinxton) | ENSG00000174282 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000174282 [Gene_View] ENSG00000174282 [Sequence] chr17:7459378-7484249 [Contig_View] ZBTB4 [Vega] |
| ICGC DataPortal | ENSG00000174282 |
| TCGA cBioPortal | ZBTB4 |
| AceView (NCBI) | ZBTB4 |
| Genatlas (Paris) | ZBTB4 |
| WikiGenes | 57659 |
| SOURCE (Princeton) | ZBTB4 |
| Genetics Home Reference (NIH) | ZBTB4 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ZBTB4 - chr17:7459378-7484249 - 17p13.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ZBTB4 - 17p13.1 [Description] (hg19-Feb_2009) |
| GoldenPath | ZBTB4 - 17p13.1 [CytoView hg19] ZBTB4 - 17p13.1 [CytoView hg38] |
| Genome Data Viewer NCBI | ZBTB4 [Mapview hg19] |
| OMIM | 612308 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB040971 AK027143 AK122826 AK122971 AY302699 |
| RefSeq transcript (Entrez) | NM_001128833 NM_020899 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ZBTB4 |
| Alternative Splicing Gallery | ENSG00000174282 |
| Gene Expression | ZBTB4 [ NCBI-GEO ] ZBTB4 [ EBI - ARRAY_EXPRESS ]
ZBTB4 [ SEEK ] ZBTB4 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ZBTB4 [ Firebrowse - Broad ] |
| Genevisible | Expression of ZBTB4 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 57659 |
| GTEX Portal (Tissue expression) | ZBTB4 |
| Human Protein Atlas | ENSG00000174282-ZBTB4 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9P1Z0 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9P1Z0 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9P1Z0 |
| Splice isoforms : SwissVar | Q9P1Z0 |
| PhosPhoSitePlus | Q9P1Z0 |
| Domaine pattern : Prosite (Expaxy) | BTB (PS50097) ZINC_FINGER_C2H2_1 (PS00028) ZINC_FINGER_C2H2_2 (PS50157) |
| Domains : Interpro (EBI) | BTB/POZ_dom SKP1/BTB/POZ_sf Znf_C2H2_sf Znf_C2H2_type |
| Domain families : Pfam (Sanger) | BTB (PF00651) |
| Domain families : Pfam (NCBI) | pfam00651 |
| Domain families : Smart (EMBL) | BTB (SM00225) ZnF_C2H2 (SM00355) |
| Conserved Domain (NCBI) | ZBTB4 |
| DMDM Disease mutations | 57659 |
| Superfamily | Q9P1Z0 |
| Human Protein Atlas [tissue] | ENSG00000174282-ZBTB4 [tissue] |
| Peptide Atlas | Q9P1Z0 |
| HPRD | 11693 |
| IPI | IPI00001835 IPI00830097 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9P1Z0 |
| IntAct (EBI) | Q9P1Z0 |
| FunCoup | ENSG00000174282 |
| BioGRID | ZBTB4 |
| STRING (EMBL) | ZBTB4 |
| ZODIAC | ZBTB4 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9P1Z0 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm chromosome cytosol regulation of transcription, DNA-templated cellular response to DNA damage stimulus methyl-CpG binding methyl-CpNpG binding nuclear body protein kinase binding protein homodimerization activity sequence-specific DNA binding negative regulation of transcription, DNA-templated metal ion binding |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm chromosome cytosol regulation of transcription, DNA-templated cellular response to DNA damage stimulus methyl-CpG binding methyl-CpNpG binding nuclear body protein kinase binding protein homodimerization activity sequence-specific DNA binding negative regulation of transcription, DNA-templated metal ion binding |
| NDEx Network | ZBTB4 |
| Atlas of Cancer Signalling Network | ZBTB4 |
| Wikipedia pathways | ZBTB4 |
| Orthology - Evolution |
|---|
| OrthoDB | 57659 |
| GeneTree (enSembl) | ENSG00000174282 |
| Phylogenetic Trees/Animal Genes : TreeFam | ZBTB4 |
| HOGENOM | Q9P1Z0 |
| Homologs : HomoloGene | ZBTB4 |
| Homology/Alignments : Family Browser (UCSC) | ZBTB4 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ZBTB4 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ZBTB4 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ZBTB4 |
| dbVar | ZBTB4 |
| ClinVar | ZBTB4 |
| 1000_Genomes | ZBTB4 |
| Exome Variant Server | ZBTB4 |
| GNOMAD Browser | ENSG00000174282 |
| Varsome Browser | ZBTB4 |
| Genetic variants : HAPMAP | 57659 |
| Genomic Variants (DGV) | ZBTB4 [DGVbeta] |
| DECIPHER | ZBTB4 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ZBTB4 |
| Mutations |
|---|
| ICGC Data Portal | ZBTB4 |
| TCGA Data Portal | ZBTB4 |
| Broad Tumor Portal | ZBTB4 |
| OASIS Portal | ZBTB4 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ZBTB4 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ZBTB4 |
| Mutations and Diseases : HGMD | ZBTB4 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | select ZBTB4 |
| DgiDB (Drug Gene Interaction Database) | ZBTB4 |
| DoCM (Curated mutations) | ZBTB4 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ZBTB4 (select a term) |
| intoGen | ZBTB4 |
| Cancer3D | ZBTB4 (select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 612308 |
| Orphanet | |
| DisGeNET | ZBTB4 |
| Medgen | ZBTB4 |
| Genetic Testing Registry | ZBTB4
|
| NextProt | Q9P1Z0 [Medical] |
| TSGene | 57659 |
| GENETests | ZBTB4 |
| Open Targets Genetics | ENSG00000174282 [validation] |
| snp3D : Map Gene to Disease | 57659 |
| BioCentury BCIQ | ZBTB4 |
| ClinGen | ZBTB4 |
| Clinical trials, drugs, therapy |
|---|
| Protein Interactions : CTD | 57659 |
| Pharm GKB Gene | PA134959224 |
| Clinical trial | ZBTB4 |
| Miscellaneous |
|---|
| canSAR (ICR) | ZBTB4 (select the gene name) |
| Harmonizome | ZBTB4 |
| DataMed Index | ZBTB4 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 23 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ZBTB4 |
| EVEX | ZBTB4 |
