Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ZCWPW2 (zinc finger CW-type and PWWP domain containing 2)

Identity

Alias_nameszinc finger, CW type with PWWP domain 2
Alias_symbol (synonym)ZCW2
Other alias
HGNC (Hugo) ZCWPW2
LocusID (NCBI) 152098
Atlas_Id 75903
Location 3p24.1  [Link to chromosome band 3p24]
Location_base_pair Starts at 28349149 and ends at 28526366 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SUCO (1q24.3) / ZCWPW2 (3p24.1)ZCWPW2 (3p24.1) / PPP4R2 (3p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;3)(q24;p24) SUCO/ZCWPW2
t(3;3)(p13;p24) ZCWPW2/PPP4R2

External links

Nomenclature
HGNC (Hugo)ZCWPW2   23574
Cards
Entrez_Gene (NCBI)ZCWPW2  152098  zinc finger CW-type and PWWP domain containing 2
AliasesZCW2
GeneCards (Weizmann)ZCWPW2
Ensembl hg19 (Hinxton)ENSG00000206559 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000206559 [Gene_View]  ENSG00000206559 [Sequence]  chr3:28349149-28526366 [Contig_View]  ZCWPW2 [Vega]
ICGC DataPortalENSG00000206559
TCGA cBioPortalZCWPW2
AceView (NCBI)ZCWPW2
Genatlas (Paris)ZCWPW2
WikiGenes152098
SOURCE (Princeton)ZCWPW2
Genetics Home Reference (NIH)ZCWPW2
Genomic and cartography
GoldenPath hg38 (UCSC)ZCWPW2  -     chr3:28349149-28526366 +  3p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZCWPW2  -     3p24.1   [Description]    (hg19-Feb_2009)
GoldenPathZCWPW2 - 3p24.1 [CytoView hg19]  ZCWPW2 - 3p24.1 [CytoView hg38]
ImmunoBaseENSG00000206559
genome Data Viewer NCBIZCWPW2 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB087877 AJ519236 BC065764 BC094696 BU508346
RefSeq transcript (Entrez)NM_001040432 NM_001324169 NM_001324170
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZCWPW2
Alternative Splicing GalleryENSG00000206559
Gene ExpressionZCWPW2 [ NCBI-GEO ]   ZCWPW2 [ EBI - ARRAY_EXPRESS ]   ZCWPW2 [ SEEK ]   ZCWPW2 [ MEM ]
Gene Expression Viewer (FireBrowse)ZCWPW2 [ Firebrowse - Broad ]
GenevisibleExpression of ZCWPW2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)152098
GTEX Portal (Tissue expression)ZCWPW2
Human Protein AtlasENSG00000206559-ZCWPW2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ504Y3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ504Y3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ504Y3
Splice isoforms : SwissVarQ504Y3
PhosPhoSitePlusQ504Y3
Domaine pattern : Prosite (Expaxy)PWWP (PS50812)    ZF_CW (PS51050)   
Domains : Interpro (EBI)PWWP_dom    ZCWPW1/ZCWPW2    Znf_CW   
Domain families : Pfam (Sanger)PWWP (PF00855)    zf-CW (PF07496)   
Domain families : Pfam (NCBI)pfam00855    pfam07496   
Conserved Domain (NCBI)ZCWPW2
DMDM Disease mutations152098
Blocks (Seattle)ZCWPW2
PDB (RSDB)4O62    4Z0O    4Z0R   
PDB Europe4O62    4Z0O    4Z0R   
PDB (PDBSum)4O62    4Z0O    4Z0R   
PDB (IMB)4O62    4Z0O    4Z0R   
Structural Biology KnowledgeBase4O62    4Z0O    4Z0R   
SCOP (Structural Classification of Proteins)4O62    4Z0O    4Z0R   
CATH (Classification of proteins structures)4O62    4Z0O    4Z0R   
SuperfamilyQ504Y3
Human Protein Atlas [tissue]ENSG00000206559-ZCWPW2 [tissue]
Peptide AtlasQ504Y3
IPIIPI00097477   IPI00926053   IPI00926447   IPI00926762   IPI00926961   
Protein Interaction databases
DIP (DOE-UCLA)Q504Y3
IntAct (EBI)Q504Y3
FunCoupENSG00000206559
BioGRIDZCWPW2
STRING (EMBL)ZCWPW2
ZODIACZCWPW2
Ontologies - Pathways
QuickGOQ504Y3
Ontology : AmiGOzinc ion binding  
Ontology : EGO-EBIzinc ion binding  
NDEx NetworkZCWPW2
Atlas of Cancer Signalling NetworkZCWPW2
Wikipedia pathwaysZCWPW2
Orthology - Evolution
OrthoDB152098
GeneTree (enSembl)ENSG00000206559
Phylogenetic Trees/Animal Genes : TreeFamZCWPW2
HOGENOMQ504Y3
Homologs : HomoloGeneZCWPW2
Homology/Alignments : Family Browser (UCSC)ZCWPW2
Gene fusions - Rearrangements
Fusion : QuiverZCWPW2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZCWPW2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZCWPW2
dbVarZCWPW2
ClinVarZCWPW2
1000_GenomesZCWPW2 
Exome Variant ServerZCWPW2
GNOMAD BrowserENSG00000206559
Varsome BrowserZCWPW2
Genetic variants : HAPMAP152098
Genomic Variants (DGV)ZCWPW2 [DGVbeta]
DECIPHERZCWPW2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZCWPW2 
Mutations
ICGC Data PortalZCWPW2 
TCGA Data PortalZCWPW2 
Broad Tumor PortalZCWPW2
OASIS PortalZCWPW2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZCWPW2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZCWPW2
Mutations and Diseases : HGMDZCWPW2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZCWPW2
DgiDB (Drug Gene Interaction Database)ZCWPW2
DoCM (Curated mutations)ZCWPW2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZCWPW2 (select a term)
intoGenZCWPW2
Cancer3DZCWPW2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZCWPW2
MedgenZCWPW2
Genetic Testing Registry ZCWPW2
NextProtQ504Y3 [Medical]
TSGene152098
GENETestsZCWPW2
Target ValidationZCWPW2
Huge Navigator ZCWPW2 [HugePedia]
snp3D : Map Gene to Disease152098
BioCentury BCIQZCWPW2
ClinGenZCWPW2
Clinical trials, drugs, therapy
Protein Interactions : CTD152098
Pharm GKB GenePA134888742
Clinical trialZCWPW2
Miscellaneous
canSAR (ICR)ZCWPW2 (select the gene name)
HarmonizomeZCWPW2
DataMed IndexZCWPW2
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZCWPW2
EVEXZCWPW2
GoPubMedZCWPW2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 10 20:44:21 CEST 2020
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