ZFAND2B (zinc finger AN1-type containing 2B)

2015-03-01  

Identity

HGNC
ZFAND2B
LOCATION
2q35
LOCUSID
130617
ALIAS
AIRAPL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 130617
MIM: 613474
HGNC: 25206
Ensembl: ENSG00000158552

Variants:

dbSNP: 130617
ClinVar: 130617
TCGA: ENSG00000158552
COSMIC: ZFAND2B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158552ENST00000289528Q8WV99
ENSG00000158552ENST00000289528A0A024R435
ENSG00000158552ENST00000409097B4DEN4
ENSG00000158552ENST00000409206Q8WV99
ENSG00000158552ENST00000409217E9PFU9
ENSG00000158552ENST00000409319B8ZZ56
ENSG00000158552ENST00000409336Q8WV99
ENSG00000158552ENST00000409336A0A024R435
ENSG00000158552ENST00000409412B8ZZ56
ENSG00000158552ENST00000409594Q8WV99
ENSG00000158552ENST00000422255E7EV05
ENSG00000158552ENST00000425849H7C491
ENSG00000158552ENST00000436556C9J1R6
ENSG00000158552ENST00000444522Q8WV99
ENSG00000158552ENST00000444522A0A024R435
ENSG00000158552ENST00000448496F8WEE4
ENSG00000158552ENST00000621130A0A087X0D9

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
194144862009AIP-1 ameliorates beta-amyloid peptide toxicity in a Caenorhabditis elegans Alzheimer's disease model.25
263373892015Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex.11
266923332016Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.9
241608172014Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex.7
242153622014Zinc finger protein in severe dry eye syndrome.1

Citation

Dessen P

ZFAND2B (zinc finger AN1-type containing 2B)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55140/zfand2b