Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZNF143 (zinc finger protein 143)

Identity

Alias_nameszinc finger protein 143 (clone pHZ-1)
Alias_symbol (synonym)SBF
pHZ-1
STAF
Other alias
HGNC (Hugo) ZNF143
LocusID (NCBI) 7702
Atlas_Id 42871
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 9460965 and ends at 9528524 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FSTL1 (3q13.33) / ZNF143 (11p15.4)MEIS2 (15q14) / ZNF143 (11p15.4)SWAP70 (11p15.4) / ZNF143 (11p15.4)
WDR74 (11q12.3) / ZNF143 (11p15.4)ZNF143 (11p15.4) / TMEM41B (11p15.4)MEIS2 15q14 / ZNF143 11p15.4
SWAP70 11p15.4 / ZNF143 11p15.4ZNF143 11p15.4 / TMEM41B 11p15.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  SWAP70/ZNF143 (11p15)
ZNF143/TMEM41B (11p15)
t(11;15)(p15;q14) MEIS2/ZNF143


External links

Nomenclature
HGNC (Hugo)ZNF143   12928
Cards
Entrez_Gene (NCBI)ZNF143  7702  zinc finger protein 143
AliasesSBF; STAF; pHZ-1
GeneCards (Weizmann)ZNF143
Ensembl hg19 (Hinxton)ENSG00000166478 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166478 [Gene_View]  ENSG00000166478 [Sequence]  chr11:9460965-9528524 [Contig_View]  ZNF143 [Vega]
ICGC DataPortalENSG00000166478
TCGA cBioPortalZNF143
AceView (NCBI)ZNF143
Genatlas (Paris)ZNF143
WikiGenes7702
SOURCE (Princeton)ZNF143
Genetics Home Reference (NIH)ZNF143
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF143  -     chr11:9460965-9528524 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF143  -     11p15.4   [Description]    (hg19-Feb_2009)
GoldenPathZNF143 - 11p15.4 [CytoView hg19]  ZNF143 - 11p15.4 [CytoView hg38]
ImmunoBaseENSG00000166478
Mapping of homologs : NCBIZNF143 [Mapview hg19]  ZNF143 [Mapview hg38]
OMIM603433   
Gene and transcription
Genbank (Entrez)AF071771 AK291133 AK297214 AK313330 AW162015
RefSeq transcript (Entrez)NM_001282656 NM_001282657 NM_003442
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF143
Cluster EST : UnigeneHs.523471 [ NCBI ]
CGAP (NCI)Hs.523471
Alternative Splicing GalleryENSG00000166478
Gene ExpressionZNF143 [ NCBI-GEO ]   ZNF143 [ EBI - ARRAY_EXPRESS ]   ZNF143 [ SEEK ]   ZNF143 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF143 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7702
GTEX Portal (Tissue expression)ZNF143
Human Protein AtlasENSG00000166478-ZNF143 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52747   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP52747  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP52747
Splice isoforms : SwissVarP52747
PhosPhoSitePlusP52747
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF143
DMDM Disease mutations7702
Blocks (Seattle)ZNF143
SuperfamilyP52747
Human Protein Atlas [tissue]ENSG00000166478-ZNF143 [tissue]
Peptide AtlasP52747
HPRD04578
IPIIPI00305316   IPI00929121   IPI01013103   IPI00853046   IPI00852701   IPI00979976   IPI00852831   IPI00852950   IPI01010037   IPI00983619   IPI01009753   IPI00852612   IPI00976507   IPI00984223   IPI00983348   
Protein Interaction databases
DIP (DOE-UCLA)P52747
IntAct (EBI)P52747
FunCoupENSG00000166478
BioGRIDZNF143
STRING (EMBL)ZNF143
ZODIACZNF143
Ontologies - Pathways
QuickGOP52747
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  regulation of transcription by RNA polymerase III  transcription by RNA polymerase II  transcription by RNA polymerase III  snRNA transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  regulation of transcription by RNA polymerase III  transcription by RNA polymerase II  transcription by RNA polymerase III  snRNA transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF143
Atlas of Cancer Signalling NetworkZNF143
Wikipedia pathwaysZNF143
Orthology - Evolution
OrthoDB7702
GeneTree (enSembl)ENSG00000166478
Phylogenetic Trees/Animal Genes : TreeFamZNF143
HOGENOMP52747
Homologs : HomoloGeneZNF143
Homology/Alignments : Family Browser (UCSC)ZNF143
Gene fusions - Rearrangements
Fusion : MitelmanMEIS2/ZNF143 [15q14/11p15.4]  [t(11;15)(p15;q14)]  
Fusion : MitelmanSWAP70/ZNF143 [11p15.4/11p15.4]  [t(11;11)(p15;p15)]  
Fusion : MitelmanZNF143/TMEM41B [11p15.4/11p15.4]  [t(11;11)(p15;p15)]  
Fusion PortalMEIS2 15q14 ZNF143 11p15.4 GBM
Fusion PortalSWAP70 11p15.4 ZNF143 11p15.4 LGG LUAD
Fusion PortalZNF143 11p15.4 TMEM41B 11p15.4 LUAD
Fusion : QuiverZNF143
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF143 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF143
dbVarZNF143
ClinVarZNF143
1000_GenomesZNF143 
Exome Variant ServerZNF143
ExAC (Exome Aggregation Consortium)ENSG00000166478
GNOMAD BrowserENSG00000166478
Varsome BrowserZNF143
Genetic variants : HAPMAP7702
Genomic Variants (DGV)ZNF143 [DGVbeta]
DECIPHERZNF143 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF143 
Mutations
ICGC Data PortalZNF143 
TCGA Data PortalZNF143 
Broad Tumor PortalZNF143
OASIS PortalZNF143 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF143  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF143
Mutations and Diseases : HGMDZNF143
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF143
DgiDB (Drug Gene Interaction Database)ZNF143
DoCM (Curated mutations)ZNF143 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF143 (select a term)
intoGenZNF143
Cancer3DZNF143(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603433   
Orphanet
DisGeNETZNF143
MedgenZNF143
Genetic Testing Registry ZNF143
NextProtP52747 [Medical]
TSGene7702
GENETestsZNF143
Target ValidationZNF143
Huge Navigator ZNF143 [HugePedia]
snp3D : Map Gene to Disease7702
BioCentury BCIQZNF143
ClinGenZNF143
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7702
Chemical/Pharm GKB GenePA37515
Clinical trialZNF143
Miscellaneous
canSAR (ICR)ZNF143 (select the gene name)
DataMed IndexZNF143
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF143
EVEXZNF143
GoPubMedZNF143
iHOPZNF143
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:16:09 CET 2019

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