ZNF185 (zinc finger protein 185 with LIM domain)

2007-02-01  

Identity

HGNC
ZNF185
LOCATION
Xq28
LOCUSID
7739
ALIAS
SCELL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7739
MIM: 300381
HGNC: 12976
Ensembl: ENSG00000147394

Variants:

dbSNP: 7739
ClinVar: 7739
TCGA: ENSG00000147394
COSMIC: ZNF185

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147394ENST00000318504O15231
ENSG00000147394ENST00000318529O15231
ENSG00000147394ENST00000324823O15231
ENSG00000147394ENST00000370268O15231
ENSG00000147394ENST00000370270O15231
ENSG00000147394ENST00000426821H0Y704
ENSG00000147394ENST00000436731H7BZT5
ENSG00000147394ENST00000447792H7C1R1
ENSG00000147394ENST00000449285O15231
ENSG00000147394ENST00000454925O15231
ENSG00000147394ENST00000535861O15231
ENSG00000147394ENST00000539731O15231

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
128739762003Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression.133
167996302007ZNF185, an actin-cytoskeleton-associated growth inhibitory LIM protein in prostate cancer.21
157311172005Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells.15
303376872019ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development.7
276554852016ZNF185 inhibits growth and invasion of lung adenocarcinoma cells through inhibition of the akt/gsk3β pathway.3
276674562016[Expression and localization of zinc finger protein 185 in sperm cells, Leydig cells and Sertoli cells of mouse testis].0
304466322018ZNF185 is a p53 target gene following DNA damage.0

Citation

Dessen P

ZNF185 (zinc finger protein 185 with LIM domain)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43836/znf185