ZNF331 (zinc finger protein 331)

2003-02-01  

Identity

HGNC
ZNF331
LOCATION
19q13.42
LOCUSID
55422
ALIAS
RITA,ZNF361,ZNF463
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55422
MIM: 606043
HGNC: 15489
Ensembl: ENSG00000130844

Variants:

dbSNP: 55422
ClinVar: 55422
TCGA: ENSG00000130844
COSMIC: ZNF331

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130844ENST00000253144Q9NQX6
ENSG00000130844ENST00000253144A0A024R4J5
ENSG00000130844ENST00000411977Q9NQX6
ENSG00000130844ENST00000411977A0A024R4J5
ENSG00000130844ENST00000449416Q9NQX6
ENSG00000130844ENST00000449416A0A024R4J5
ENSG00000130844ENST00000502248E7EV14
ENSG00000130844ENST00000502616Q71QC5
ENSG00000130844ENST00000504493Q9NQX6
ENSG00000130844ENST00000504493A0A024R4J5
ENSG00000130844ENST00000505426Q71QC9
ENSG00000130844ENST00000505949E7ETJ5
ENSG00000130844ENST00000509585D6RH27
ENSG00000130844ENST00000511154Q9NQX6
ENSG00000130844ENST00000511154A0A024R4J5
ENSG00000130844ENST00000511567E7EPT0
ENSG00000130844ENST00000511593Q9NQX6
ENSG00000130844ENST00000511593A0A024R4J5
ENSG00000130844ENST00000512387Q9NQX6
ENSG00000130844ENST00000512387A0A024R4J5
ENSG00000130844ENST00000513265E7EPG5
ENSG00000130844ENST00000513999Q9NQX6
ENSG00000130844ENST00000513999A0A024R4J5
ENSG00000130844ENST00000514374E7EWU7
ENSG00000130844ENST00000648122Q9NQX6
ENSG00000130844ENST00000648122A0A024R4J5
ENSG00000130844ENST00000648236Q9NQX6
ENSG00000130844ENST00000648236A0A024R4J5
ENSG00000130844ENST00000648397Q9NQX6
ENSG00000130844ENST00000648397A0A024R4J5
ENSG00000130844ENST00000648511Q9NQX6
ENSG00000130844ENST00000648511A0A024R4J5
ENSG00000130844ENST00000649326Q9NQX6
ENSG00000130844ENST00000649326A0A024R4J5

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
249480442015The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers.26
223706392013Zinc-finger protein 331, a novel putative tumor suppressor, suppresses growth and invasiveness of gastric cancer.22
146103502003A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas.7
290753582017Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.5
259298672015Methylation of ZNF331 Promotes Cell Invasion and Migration in Human Esophageal Cancer.4
261348732015RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling.4
291223592018Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.3
313538152019RITA modulates cell migration and invasion by affecting focal adhesion dynamics.3
298540112018Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer.2

Citation

Dessen P

ZNF331 (zinc finger protein 331)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42879/znf331