ZNF366 (zinc finger protein 366)

2011-03-01  

Identity

HGNC
ZNF366
LOCATION
5q13.2
LOCUSID
167465
ALIAS
DC-SCRIPT,DCSCRIPT
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 167465
MIM: 610159
HGNC: 18316
Ensembl: ENSG00000178175

Variants:

dbSNP: 167465
ClinVar: 167465
TCGA: ENSG00000178175
COSMIC: ZNF366

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178175ENST00000318442Q8N895
ENSG00000178175ENST00000414109F8W732
ENSG00000178175ENST00000514477D6R9P7

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
170854772006ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.25
234404192013DC-SCRIPT regulates glucocorticoid receptor function and expression of its target GILZ in dendritic cells.13
226152052012Dendritic cell-specific transcript: dendritic cell marker and regulator of TLR-induced cytokine production.11
195254782009Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.10
195254782009Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.10
163939962006Identification and characterization of DC-SCRIPT, a novel dendritic cell-expressed member of the zinc finger family of transcriptional regulators.9
261703892015DC-SCRIPT Regulates IL-10 Production in Human Dendritic Cells by Modulating NF-κBp65 Activation.8
211220992010Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study.6
204783642010Crosstalk and DC-SCRIPT: expanding nuclear receptor modulation.5

Citation

Dessen P

ZNF366 (zinc finger protein 366)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52103/znf366