ZNF418 (zinc finger protein 418)

2018-11-01  

Identity

HGNC
ZNF418
LOCATION
19q13.43
LOCUSID
147686
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 147686
HGNC: 20647
Ensembl: ENSG00000196724

Variants:

dbSNP: 147686
ClinVar: 147686
TCGA: ENSG00000196724
COSMIC: ZNF418

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196724ENST00000396147Q8TF45
ENSG00000196724ENST00000425570J3KQR4
ENSG00000196724ENST00000593296M0R1R2
ENSG00000196724ENST00000595569M0QX21
ENSG00000196724ENST00000595830Q8TF45
ENSG00000196724ENST00000599852M0QX82
ENSG00000196724ENST00000600989M0QYW9
ENSG00000196724ENST00000601593M0QXB3
ENSG00000196724ENST00000616958Q8TF45

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
180847232008ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway.12
292702392017Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).10
290651702017Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis.3
313379802019miR-1204 promotes hepatocellular carcinoma progression through activating MAPK and c-Jun/AP1 signaling by targeting ZNF418.3

Citation

Dessen P

ZNF418 (zinc finger protein 418)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57738/znf418