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ZNF446 (zinc finger protein 446)

Identity

Alias_symbol (synonym)ZKSCAN20
FLJ20626
ZSCAN52
Other aliasZSCAN30
HGNC (Hugo) ZNF446
LocusID (NCBI) 55663
Atlas_Id 76164
Location 19q13.43  [Link to chromosome band 19q13]
Location_base_pair Starts at 58477179 and ends at 58489533 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SEC61G (7p11.2) / ZNF446 (19q13.43)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF446   21036
Cards
Entrez_Gene (NCBI)ZNF446  55663  zinc finger protein 446
AliasesZKSCAN20; ZSCAN30; ZSCAN52
GeneCards (Weizmann)ZNF446
Ensembl hg19 (Hinxton)ENSG00000083838 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000083838 [Gene_View]  ENSG00000083838 [Sequence]  chr19:58477179-58489533 [Contig_View]  ZNF446 [Vega]
ICGC DataPortalENSG00000083838
TCGA cBioPortalZNF446
AceView (NCBI)ZNF446
Genatlas (Paris)ZNF446
WikiGenes55663
SOURCE (Princeton)ZNF446
Genetics Home Reference (NIH)ZNF446
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF446  -     chr19:58477179-58489533 +  19q13.43   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF446  -     19q13.43   [Description]    (hg19-Feb_2009)
GoldenPathZNF446 - 19q13.43 [CytoView hg19]  ZNF446 - 19q13.43 [CytoView hg38]
ImmunoBaseENSG00000083838
Mapping of homologs : NCBIZNF446 [Mapview hg19]  ZNF446 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000633 AK026153 AK310384 AL122108 AL833955
RefSeq transcript (Entrez)NM_001304453 NM_017908
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF446
Cluster EST : UnigeneHs.710284 [ NCBI ]
CGAP (NCI)Hs.710284
Alternative Splicing GalleryENSG00000083838
Gene ExpressionZNF446 [ NCBI-GEO ]   ZNF446 [ EBI - ARRAY_EXPRESS ]   ZNF446 [ SEEK ]   ZNF446 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF446 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55663
GTEX Portal (Tissue expression)ZNF446
Human Protein AtlasENSG00000083838-ZNF446 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWS9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWS9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWS9
Splice isoforms : SwissVarQ9NWS9
PhosPhoSitePlusQ9NWS9
Domaine pattern : Prosite (Expaxy)SCAN_BOX (PS50804)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    SCAN_dom    SCAN_sf    Zfp18/Zfp446    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    SCAN (PF02023)   
Domain families : Pfam (NCBI)pfam01352    pfam02023   
Domain families : Smart (EMBL)KRAB (SM00349)  SCAN (SM00431)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF446
DMDM Disease mutations55663
Blocks (Seattle)ZNF446
SuperfamilyQ9NWS9
Human Protein Atlas [tissue]ENSG00000083838-ZNF446 [tissue]
Peptide AtlasQ9NWS9
HPRD07934
IPIIPI00016671   IPI00386169   IPI01012786   IPI00168548   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWS9
IntAct (EBI)Q9NWS9
FunCoupENSG00000083838
BioGRIDZNF446
STRING (EMBL)ZNF446
ZODIACZNF446
Ontologies - Pathways
QuickGOQ9NWS9
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  extracellular space  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  extracellular space  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF446
Atlas of Cancer Signalling NetworkZNF446
Wikipedia pathwaysZNF446
Orthology - Evolution
OrthoDB55663
GeneTree (enSembl)ENSG00000083838
Phylogenetic Trees/Animal Genes : TreeFamZNF446
HOGENOMQ9NWS9
Homologs : HomoloGeneZNF446
Homology/Alignments : Family Browser (UCSC)ZNF446
Gene fusions - Rearrangements
Fusion : QuiverZNF446
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF446 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF446
dbVarZNF446
ClinVarZNF446
1000_GenomesZNF446 
Exome Variant ServerZNF446
ExAC (Exome Aggregation Consortium)ENSG00000083838
GNOMAD BrowserENSG00000083838
Varsome BrowserZNF446
Genetic variants : HAPMAP55663
Genomic Variants (DGV)ZNF446 [DGVbeta]
DECIPHERZNF446 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF446 
Mutations
ICGC Data PortalZNF446 
TCGA Data PortalZNF446 
Broad Tumor PortalZNF446
OASIS PortalZNF446 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF446  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF446
Mutations and Diseases : HGMDZNF446
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF446
DgiDB (Drug Gene Interaction Database)ZNF446
DoCM (Curated mutations)ZNF446 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF446 (select a term)
intoGenZNF446
Cancer3DZNF446(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF446
MedgenZNF446
Genetic Testing Registry ZNF446
NextProtQ9NWS9 [Medical]
TSGene55663
GENETestsZNF446
Target ValidationZNF446
Huge Navigator ZNF446 [HugePedia]
snp3D : Map Gene to Disease55663
BioCentury BCIQZNF446
ClinGenZNF446
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55663
Chemical/Pharm GKB GenePA134863395
Clinical trialZNF446
Miscellaneous
canSAR (ICR)ZNF446 (select the gene name)
DataMed IndexZNF446
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF446
EVEXZNF446
GoPubMedZNF446
iHOPZNF446
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:14:09 CEST 2019

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