ZRANB2 (zinc finger RANBP2-type containing 2)

2014-03-01  

Identity

HGNC
ZRANB2
LOCATION
1p31.1
LOCUSID
9406
ALIAS
ZIS,ZIS1,ZIS2,ZNF265
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9406
MIM: 604347
HGNC: 13058
Ensembl: ENSG00000132485

Variants:

dbSNP: 9406
ClinVar: 9406
TCGA: ENSG00000132485
COSMIC: ZRANB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132485ENST00000254821O95218
ENSG00000132485ENST00000370920O95218
ENSG00000132485ENST00000611683O95218

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
236660632013ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome.15
126576332003The structure of the zinc finger domain from human splicing factor ZNF265 fold.11
190523802008Crystallization of a ZRANB2-RNA complex.1
319431182020ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin.0

Citation

Dessen P

ZRANB2 (zinc finger RANBP2-type containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53842/zranb2