ZSCAN4 (zinc finger and SCAN domain containing 4)

2016-05-01 Affiliation

Identity

HGNC

ZSCAN4

LOCATION

19q13.43

LOCUSID

201516

ALIAS

ZNF494

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 201516
MIM: 613419
HGNC: 23709
Ensembl: ENSG00000180532

Variants:

dbSNP: 201516
ClinVar: 201516
TCGA: ENSG00000180532
COSMIC: ZSCAN4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000180532	ENST00000318203	Q8NAM6
ENSG00000180532	ENST00000612521	Q8NAM6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
29712904	2018	The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1.	8
24840609	2014	Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status.	7
26403970	2015	ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.	5
27699653	2017	Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis.	4
29477841	2018	ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20.	3
27699651	2017	Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos.	2

Citation

Dessen P

ZSCAN4 (zinc finger and SCAN domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55746/zscan4