BCAN/NTRK1 (1q23)

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

1q23.1

Gene name

Location

1q23.1

Highly cited references

Pubmed IDYearTitleCitations
286958882017Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.31
298726942017Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.22
296542292018Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.20
295327922018Author Correction: Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.1
348630952021Discovery of clinically relevant fusions in pediatric cancer.0

Bibliography

Pubmed IDLast YearTitleAuthors
239174012013The integrated landscape of driver genomic alterations in glioblastoma.Frattini V et al
242619842013Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data.Shah N et al

Citation

Jean-Loup Huret ; Philippe Dessen

BCAN/NTRK1 (1q23)

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/103943/bcan-ntrk1-(1q23)