t(1;19)(q22;q13) LMNA/FOSB

Identity

Atlas_Id	104286
Phylum	Nervous system: Central Nervous system::
WHO/OMS Classification	Nervous system
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Central Nervous system: Meningioma

Genes involved and Proteins

Gene Name	LMNA
Location	1q22

Gene Name	FOSB
Location	19q13.32

Bibliography

Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, Beroukhim R

Nat Genet 2013 Mar;45(3):285-9

PMID 23334667

Translocations implicated (Data extracted from papers in the Atlas)

	t(1;19)(q22;q13) LMNA/FOSB

External links

Mitelman database	t(1;19)(q22;q13) [CaseList]     t(1;19)(q22;q13) [Transloc - MCList]   LMNA/FOSB Fusion - MCList]
COSMIC	[ LMNA ]   [ FOSB ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(1;19)(q22;q13) LMNA/FOSB

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 13 22:23:56 CET 2019

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