t(2;5)(q35;q31) FN1/FGF1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

2q35

Gene name

Location

5q31.3

Highly cited references

Pubmed IDYearTitleCitations
274435182016Characterization of FN1-FGFR1 and novel FN1-FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors.35
294460102018Phosphaturic mesenchymal tumors: what an endocrinologist should know.10
317923552020Frequent overexpression of klotho in fusion-negative phosphaturic mesenchymal tumors with tumorigenic implications.5
331514122021Clinicopathologic and molecular features of six cases of phosphaturic mesenchymal tumor.0

Bibliography

Pubmed IDLast YearTitleAuthors
274435182016Characterization of FN1-FGFR1 and novel FN1-FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors.Lee JC et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(2;5)(q35;q31) FN1/FGF1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/105466/t(2;5)(q35;q31)-fn1-fgf1