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t(8;12)(q22;q13) PTDSS1/SPRYD3

Written08-2018Jean-Loup Huret, Philippe Dessen

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Atlas_Id 107845
Phylum Male organs: Prostate::
WHO/OMS Classification Male organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Prostate: Adenocarcinoma

Genes involved and Proteins

Gene NamePTDSS1
Location 8q22.1

Gene NameSPRYD3
Location 12q13.13


Poly-gene fusion transcripts and chromothripsis in prostate cancer
Wu C, Wyatt AW, McPherson A, Lin D, McConeghy BJ, Mo F, Shukin R, Lapuk AV, Jones SJ, Zhao Y, Marra MA, Gleave ME, Volik SV, Wang Y, Sahinalp SC, Collins CC
Genes Chromosomes Cancer 2012 Dec;51(12):1144-53
PMID 22927308

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(q22;q13) PTDSS1/SPRYD3

External links

Mitelman database t(8;12)(q22;q13) [Fusion]     t(8;12)(q22;q13) [Cytogenetics Case]
Disease databaset(8;12)(q22;q13) PTDSS1/SPRYD3
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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