t(9;9)(q21;q34) NACC2/NTRK2

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

NACC2

Location

9q34.3

Gene name

NTRK2

Location

9q21.33

Highly cited references

Pubmed IDYearTitleCitations
345180392022Detection of NTRK fusions in glioblastoma: fluorescent in situ hybridisation is more useful than pan-TRK immunohistochemistry as a screening tool prior to RNA sequencing.1
330933552021Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers.1
337688712021NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling.1

Bibliography

Pubmed IDLast YearTitleAuthors
238175722013Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Jones DT et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(9;9)(q21;q34) NACC2/NTRK2

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/108486/t(9;9)(q21;q34)-nacc2-ntrk2