t(9;15)(q34;q14) BRD3/NUTM1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

BRD3

Location

9q34.2

Gene name

NUTM1

Location

15q14

Highly cited references

Pubmed IDYearTitleCitations
293567242018NUTM1 Gene Fusions Characterize a Subset of Undifferentiated Soft Tissue and Visceral Tumors.32
323285622020An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients.28
344823322021Cutaneous Primary NUT Carcinoma With BRD3-NUTM1 Fusion.2
353720032022NUT Carcinoma: Clinicopathologic Features, Molecular Genetics and Epigenetics.1
344693322021Reply to: Expanding the Spectrum of Primary Cutaneous Carcinoma With BRD3-NUTM1 Fusion.1
356234652022NUT carcinoma, an under-recognized malignancy: a clinicopathologic and molecular series of 6 cases showing a subset of patients with better prognosis and a rare ZNF532::NUTM1 fusion.0
346721282022BRD3-NUTM1-expressing NUT carcinoma of lung on endobronchial ultrasound-guided transbronchial needle aspiration cytology, a diagnostic pitfall.0

Bibliography

Pubmed IDLast YearTitleAuthors
179345172008BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.French CA et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(9;15)(q34;q14) BRD3/NUTM1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/108329/t(9;15)(q34;q14)-brd3-nutm1