t(10;10)(q21;q26) FGFR2/BICC1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

10q26.13

Gene name

Location

10q21.1

Bibliography

Pubmed IDLast YearTitleAuthors
235589532013Identification of targetable FGFR gene fusions in diverse cancers.Wu YM et al
241228102014Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.Arai Y et al
245507392014Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.Borad MJ et al
245630762014New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.Ross JS et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(10;10)(q21;q26) FGFR2/BICC1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/100197/t(10;10)(q21;q26)-fgfr2-bicc1