| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 102538 |
| Phylum | Female organs: Breast:: |
| WHO/OMS Classification | Female organs |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Breast: Adenocarcinoma |
| Genes involved and Proteins |
| Gene Name | PGAP3 |
| Location | 17q12 |
| Gene Name | PPM1D |
| Location | 17q23.2 |
| Bibliography |
| Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer |
| Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM |
| Nat Med 2011 Nov 20;17(12):1646-51 |
| PMID 22101766 |
| Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer |
| Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, Chinnaiyan AM, Kumar-Sinha C |
| Neoplasia 2012 Aug;14(8):702-8 |
| PMID 22952423 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(17;17)(q12;q23) PGAP3/PPM1D | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Wed Nov 13 22:46:56 CET 2019 |
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