inv(3)(q21q26):t(3;3)(q21;q26):t(3;3)(q26;q21) GATA2/MECOM

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

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Genes Involved and Proteins

Gene name
GATA2
Location
3q21.3
Gene name
MECOM
Location
3q26.2

Highly cited references

Pubmed IDYearTitleCitations
305768682019t(3;8)(q26.2;q24) Often Leads to MECOM/MYC Rearrangement and Is Commonly Associated with Therapy-Related Myeloid Neoplasms and/or Disease Progression.4
319026942020Secondary acquisition of BCR-ABL1 fusion in de novo GATA2-MECOM positive acute myeloid leukemia with subsequent emergence of a rare KMT2A-ASXL2 fusion.1
336478142021BCR-ABL1 positive AML or CML in blast crisis? A pediatric case report with inv(3) and t(9;22) in the initial clone.0

Bibliography

No bibliography items were found for this article.

Summary

Fusion gene

GATA2/MECOM GATA2 (3q21.3) MECOM (3q26.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

inv(3)(q21q26):t(3;3)(q21;q26):t(3;3)(q26;q21) GATA2/MECOM

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2744/inv(3)(q21q26)-t(3;3)(q21;q26)-t(3;3)(q26;q21)-gata2-mecom