t(11;17)(q23;p11) KMT2A/TOP3A

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloid leukemia, NOS

Genes Involved and Proteins

Gene name
KMT2A
Location
11q23.3
Gene name
TOP3A
Location
17p11.2

Bibliography

Pubmed IDLast YearTitleAuthors
220506352012TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia.Herbaux C et al
236289582013The MLL recombinome of acute leukemias in 2013.Meyer C et al

Summary

Fusion gene

KMT2A/TOP3A KMT2A (11q23.3) TOP3A (17p11.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(11;17)(q23;p11) KMT2A/TOP3A

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/1621/t(11;17)(q23;p11)-kmt2a-top3a