| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 101316 |
| Phylum | Nervous system: Central Nervous system:: |
| WHO/OMS Classification | Nervous system |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma |
| Genes involved and Proteins |
| Gene Name | PPM1H |
| Location | 12q14.1 |
| Gene Name | MDM2 |
| Location | 12q15 |
| Bibliography |
| Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data |
| Shah N, Lankerovich M, Lee H, Yoon JG, Schroeder B, Foltz G |
| BMC Genomics 2013 Nov 22;14:818 |
| PMID 24261984 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(12;12)(q14;q15) PPM1H/MDM2 | |
| External links |
| Mitelman database | t(12;12)(q14;q15) [Fusion] t(12;12)(q14;q15) [Cytogenetics Case] |
| COSMIC | [ PPM1H ] [ MDM2 ] |
| Disease database | t(12;12)(q14;q15) PPM1H/MDM2 |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Jul 13 11:22:11 CEST 2020 |
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